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. 2022 Jan 4;119(1):e2107763119. doi: 10.1073/pnas.2107763119

Fig. 4.

Fig. 4.

Different protocols for the curvature change. (A) Instantaneous: The target filament radius changes globally throughout the filament to Rtarget/Rcell, as indicated in the key, within a single time step. (B) Sequential: The filament curvature change starts at one end of the filament and propagates at a rate vcurv to the other end, here shown for Rtarget/Rcell=5.5%. (C) Randomized: Random bonds along the filament constrict at a rate vcurv, here shown for Rtarget/Rcell=5.5%. In all the protocols, once the entire filament has transitioned, it is disassembled from both ends at a rate vdis. The value of vdis does not influence the division curves (SI Appendix, Fig. S4). A–C, Right compare the normalized diameter of the cell at the midzone as a function of time. We selected only simulations that led to division and averaged over simulation seeds and different disassembly rates.