TABLE 2.

Change in Plasma HIV-1 RNA From Baseline at Day 7 After Single-Dose Administration of MK-8507 in Treatment-Naive Individuals With HIV-1 Infection and Historical Data From Treatment-Naive Individuals Administered Placebo

	Historical Placebo	MK-8507 (40 mg)	MK-8507 (80 mg)	MK-8507 (600 mg)
	(N = 20)	(n = 6)	(n = 6)	(n = 6)
LS mean
log10 copies/mL (95% CI)	−0.03 (−0.13 to 0.08)	−1.22 (−1.52 to −0.91)	−1.50 (−1.80 to −1.19)	−1.53 (−1.84 to −1.23)
Posterior mean adjusted by historical placebo
log10 copies/mL	N/A	−1.24	−1.53	−1.56

CI, confidence interval; LS, least squares.