TABLE 4.

Predicted human PK parameters of MK-2075 represented as median and 90% CI.

PK parameter	Median predicted value	90% confidence interval
CL (ml/min/kg)	0.402	0.368–0.440
V1 (L/kg)	0.063	0.055–0.071
V2 (L/kg)	0.130	0.114–0.148
CLD (ml/min/kg)	0.312	0.256–0.382
Terminal T1/2 (h)	9.5	8.9–10.1
Effective T1/2 (h)	5.5	5.2–6.0