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. 2021 Nov 22;1(8):100120. doi: 10.1016/j.crmeth.2021.100120

Figure 1.

Figure 1

scPOST simulates single-cell datasets to estimate power to detect differential abundance in a cluster between conditions

scPOST comprises three steps: data-driven parameter estimation, dataset simulation, and association testing. scPOST models gene expression variation (left) and cluster frequency variation (right).