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. 2020 Dec 22;2(2):355–364. doi: 10.34067/KID.0004772020

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Figure 8. — Changes in glycolysis enzymes and hypoxia markers during transition to CKD after ischemia-reperfusion injury. (A) Western blot showing increases in glycolytic enzyme protein expression during progression to CKD after ischemia/reperfusion injury (IRI). (B) Western blot showing increases in hypoxia markers after IRI. HK2, Hexokinase 2; PFKP, Phosphofructokinase platelet isoform; PFKFB3, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphate-3; PKM2, Pyruvate kinase M2; PKLR, pyruvate kinase liver/RBC isoform; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; CA9, carbonic anhydrase 9; SD, SD208, a TGF-β receptor antagonist. Nephrectomy control 14 days after sham left-kidney ischemia (14 days neph ctrl). Figure is from ref. (46) with permission.