Table 2.

Initial infusion rate (ml/h) of 136 mM CaCl₂ in 0.9% saline for goal systemic ionized Ca 1.15 mM

Effluent Flow Rate (ml/hr)	0.0–0.7 g/dl	0.8–1.2 g/dl	1.3–1.7 g/dl	1.8–2.2 g/dl	2.3–2.7 g/dl	2.8–3.2 g/dl	3.3–3.7 g/dl	3.8–4.2 g/dl	4.3–4.7 g/dl	4.8–5.2 g/dl
≤2100	28	29	30	31	32	32	33	34	35	36
2101–2500a	34	35	36	37	38	39	40	41	42	43
2501–2850	39	41	42	43	44	45	47	48	49	50
2851–3250	45	47	48	50	51	52	53	55	55	57
3251–3650	51	52	54	56	57	58	60	61	62	64
3651–4000a	56	58	60	62	63	65	67	68	69	71
4001–4400	62	64	66	68	69	71	73	75	76	78
4401–4750	68	70	72	74	76	78	80	82	83	85
4751–5150	72	74	77	79	81	83	85	87	89	91
5151–5500	76	78	81	84	85	88	90	92	94	97
5501–5850a	79	82	85	87	90	92	94	97	99	101

In patients with citrate metabolism presumed absent, the initial QCa is chosen from Table 2 on the basis of the systemic albumin level and the total effluent flow rate (≈QACDA+QD+QRF). The effect of any net ultrafiltration on QCa can be neglected. Precalculated, plasma clearance-based Ca-infusion dosing is largely independent of the intake blood Hct level if the systemic hemoglobin (Hb) <14 g/dl and the fixed post-CVVHDF-RCA flow settings are selected from Table 1. To target a higher systemic iCa of 1.3 mM (at the ICU team’s discretion) the initial Ca-infusion rate derived from Table 2 can be multiplied by 1.13. QCa, calcium infusion rate; QACDA, acid citrate dextrose anticoagulant infusion rate; QD, dialysate flow rate; QRF, replacement fluid flow rate.

^aPatients included in this study were treated using one of these rows.