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. 2020 Dec 4;2(2):312–324. doi: 10.34067/KID.0001182019

Table 5.

Risk factors for biopsy specimen–proven acute rejection after kidney transplant in recipients with polycystic kidney disease

Variable Hazard Ratio (95% CI) P Value
Age (per decade) 0.79 (0.62 to 1.01) 0.06
Female sex 1.64 (1.07 to 2.50) 0.02a
Non-White race 1.26 (0.65 to 2.47) 0.49
BMI (per 1 kg/m2 higher BMI) 1.04 (1.01 to 1.08) 0.02a
Dialysis before transplantation 1.27 (0.79 to 2.10) 0.33
Dialysis duration 1.00 (0.99 to 1.01) 0.82
Coronary artery disease 2.37 (1.47 to 3.84) <0.001a
Congestive heart failure 0.74 (0.32 to 1.72) 0.48
Polycystic liver disease 1.25 (0.79 to 1.84) 0.39
Deceased donor 0.92 (0.59 to 1.44) 0.72
Donor age 1.00 (0.85 to 1.16) 0.96
Prior kidney transplantation 2.59 (1.38 to 4.87) 0.003a
Induction treatment
 Basiliximab Reference
 Thymoglobulinb 0.82 (0.45 to 1.49) 0.50
 Alemtuzumab 1.38 (0.81 to 2.33) 0.23
 Other 0.13 (0.03 to 0.62) 0.01a
 None 0.64 (0.19 to 2.14) 0.46
Calcineurin-inhibitor maintenance
 Tacrolimus Reference
 Cyclosporine 0.86 (0.53 to 1.37) 0.52
 None 1.79 (0.97 to 3.32) 0.06a
Mycophenolate maintenance 0.33 (0.14 to 0.73) 0.006a
HLA mismatch
 0–2 Reference
 3–4 2.30 (1.21 to 4.37) 0.01a
 5–6 4.07 (2.10 to 7.92) <0.001a
Nephrectomy at transplantation 1.17 (0.74 to 1.84) 0.49

BMI, body mass index.

a

P<0.05.

b

Rabbit anti-thymocyte globulin.