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. 2015 Oct 9;2015(10):CD010790. doi: 10.1002/14651858.CD010790.pub2

Sayag 2008.

Methods "Consecutive series of patients presenting sickle cell disease were included in a prospective comparative clinical trial for argon laser photocoagulation." Described as randomised but no further information on the methods were reported.
Participants 73 eyes of 101 participants.
Interventions Peripheral focal scatter laser photocoagulation (n = 38) using argon green laser. Spot size 300 to 500 µm, 0.1 second duration with mild whitening of retina. Burns were placed around all sea fans without treating the sea fans or its feeder vessels directly, spaced approximately one burn diameter apart and usually placed from 2 disc diameters anterior to the sea fan and 2 clock hours to each of its sides.
Control group = no intervention (n = 35)
Outcomes 1. Disease progression defined by an increased size of existing lesion associated with leakage.
2. Disease regression defined by reduction of sea fan size, no perfusion or leakage on FFA.
3. Complications
Notes In the 'Methods' section, it was stated that each participant was randomised to a treatment or no treatment group. However, no other information was provided, so we were not able to fully assess eligibility.

FFA: fundus fluorescein angiography
 RCT: randomised controlled trial
 µm: micrometre