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. 2022 Jan 5;60(1):119–130. doi: 10.1080/13880209.2021.2019281

Figure 8.

Figure 8.

SHD promoted the phosphorylation of PI3k, Akt and CREB expression, and decreased TNF-α and IL6 expression. (A) The expression of p-PI3k, p-Akt, p-CREB, TNF-α and IL6 was detected by Western blotting. (B) SHD treatment increased the phosphorylation of PI3k. (C) SHD treatment increased the phosphorylation of Akt. (D) The expression of p-CREB1 was increased by treatment with SHD. (E) The expression of TNF-α was decreased by treatment with SHD. (F) SHD treatment mediated IL-6 expression compared with that in the untreated OGD group. n = 6, #p < 0.05, compared with the control group; *p < 0.05, **p < 0.01, compared with the OGD group.