Table 2.
Summary of statistical analyses to determine attribute criticality, statistically significant values are shown in green
| Modification | P-value F1 v F4 40°C | P-value F1 v F1 | P-value F2 v F4 (40°C) | R2 (40°C) |
Slope | RSD F1 (40°C) |
|---|---|---|---|---|---|---|
| N301+ A2S2F | 0.000 | 0.002 | 0.000 | 0.756 | 0.079 | 0.239 |
| N301+ A2G1F | 0.000 | 0.001 | 0.000 | 0.933 | 1.603 | 0.067 |
| N301+ A2G2F | 0.000 | 0.000 | 0.000 | 0.832 | 0.647 | 0.065 |
| N301+ A1G0F | 0.000 | 0.000 | 0.008 | 0.791 | −0.122 | 0.098 |
| ~P231 + 122.0938 | 0.000 | 0.481 | 0.199 | 0.817 | 1.036 | 0.099 |
| N301+ A1G1F | 0.000 | 0.000 | 0.024 | 0.744 | −0.090 | 0.228 |
| D284+ isomerization | 0.000 | 0.000 | 0.632 | 0.684 | 0.017 | 0.230 |
| N301+ A2G0 | 0.000 | 0.000 | 0.001 | 0.803 | 0.056 | 0.159 |
| N301+ M5 | 0.000 | 0.002 | 0.000 | 0.696 | −0.431 | 0.022 |
| N301+ A2G0F | 0.001 | 0.969 | 0.000 | 0.771 | −1.878 | 0.108 |
| N388+ deamidation | 0.002 | 0.000 | 0.572 | 0.418 | 0.035 | 0.217 |
| ~P231 + 120.0774 | 0.004 | 0.116 | 0.098 | 0.956 | −1.546 | 0.490 |
| W90+ double oxidation | 0.004 | 0.594 | 0.589 | 0.664 | −0.028 | 0.212 |
| N329+ deamidation | 0.006 | 0.002 | 0.022 | 0.796 | −1.857 | 0.181 |
| K364-65.0537 | 0.007 | 0.142 | 0.416 | 0.677 | −1.197 | 0.170 |
| W47+ double oxidation | 0.012 | 0.884 | 0.459 | 0.714 | −0.036 | 0.199 |
| M256+ carboxymethylation | 0.014 | 0.014 | 0.362 | 0.762 | 0.023 | 0.242 |
| ~Y86-44.0359 | 0.016 | 0.000 | 0.264 | 0.892 | 0.007 | 0.075 |
| ~W106+ double oxidation | 0.019 | 0.018 | 0.393 | 0.825 | −0.102 | 0.163 |