Figure 2.
Ad-SF7-Fc induces a proinflammatory cytokine and IFN response
(A) BALB/c mice were injected I.V. with 1 × 1010 v.p. of Ad-null, Ad-SF7-Fc, or not injected (naive) and 6 h later spleens were collected for RNA analysis. (B) Plasma levels of IL-12(p40) and MIP-1β were compared across treatment groups. All data presented as mean ± standard error of the mean and representative of a single experiment. Groups compared with one-way ANOVA with Tukey's multiple comparison test. ∗∗p < 0.01; ∗∗∗p < 0.001; ∗∗∗∗p < 0.0001; n.s. = not significant.