Table 2.

Mass spectrometry-detected proteins and associated DM-related pathways identified by IPA enriched in PDAC.

Pathway	P value	Genes coding for identified proteins
Glucose metabolism disorder	1.19×10−13	ADIPOQ,AGT,AHSG,ALB,AMBP,APOB,APOC3,APOD, APOE,APOM,C3,C4A/C4B,C5,CFB,CFD,CLEC3B,CLU, CRP,F10,F2,FCGR3A/FCGR3B,GPLD1,HBB,HP,LBP, PON1,PPIA,RBP4,SERPINC1,SERPIND1,SERPINF1, SHBG,TF,THBS1,TNXB
Metabolism of protein	1.11×10−12	AFM,AGT,AHSG,ALB,APCS,APOA2,APOA4,APOB, APOE,C1S,C3,C4A/C4B,C4BPA,CLU,CP,CST3,F2,F5, FGA,GPLD1,GSN,IGFALS,IGFBP3,ITIH2,KLKB1,KNG1,PROC,SAA1,SERPINA1,SERPINA10,SERPINC1, SERPIND1,TF,THBS1
Diabetes mellitus	7.59×10−12	ADIPOQ,AGT,AHSG,ALB,AMBP,APOB,APOC3,APOD, APOE,APOM,C3,C4A/C4B,C5,CFB,CLEC3B,CLU, CRP,F10,FCGR3A/FCGR3B,GPLD1,HBB,HP,PON1,PPIA,RBP4,SERPINC1,SERPIND1,SERPINF1,SHBG,TF,TNXB

DM, diabetes mellitus; IPA, Ingenuity Pathway Analysis.