Figure 2.

Visualization of immune cell types in glioblastoma tissue sections of patients after treatment with anti-epidermal growth factor receptor immunoliposomes loaded with doxorubicin (anti-EGFR ILs-dox).

(A) Representative mass cytometric images for patient 2 (left), patient 3 (center), and patient 5 (right) are shown. (B) Quantification of different cell populations including macrophages (CD68 cells), cytotoxic lymphocytes (GranzB), and proliferating cells (Ki67). Frequencies were determined as percentage of total cells. Differences were statistically analyzed by one-way analysis of variance testing. ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001. ns, not significant.