Table 1.

Patient and disease characteristics

Patient	Age at diagnosis, years	Gender	EGFR amplification	IDH mutation	LOH 1p/19q	Methylation class	MGMT-promoter methylation
1	59	Male	Yes	IDH wt	No	RTK II	Methylated
2	44	Female	Yes	IDH wt	No	RTK II	Not methylated
3	50	Male	Yes	IDH wt	No	RTK II	Not methylated
4	64	Male	Yes	IDH wt	No	RTK II	Not methylated
5	60	Female	Yes	IDH wt	No	RTK II	Methylated
6	63	Male	Yes	IDH wt	No	Mesenchymal	Methylated
7	61	Male	Yes	IDH wt	No	Unclear	Not methylated
8	58	Male	Yes	IDH wt	No	Mesenchymal	Not methylated
9	50	Male	Yes	IDH wt	No	Mesenchymal	Methylated

EGFR, epidermal growth factor receptor; IDH, isocitrate dehydrogenase; LOH 1p/19q, loss of heterozygosity on chromosome 1 (1p) and 19 (19q); MGMT, O6-methylguanine-DNA methyltransferase; RTK, receptor tyrosine kinase; wt, wild type.