Table 1.
Description of infants with severe bronchiolitis according to profiles (A-D) identified through latent class analysis in three cohort studies.
| Variables used in latent class analysis | All | Profiles |
P-value | |||
|---|---|---|---|---|---|---|
| A | B | C | D | |||
| n = 3081 | n = 388 (13%) | n = 1064 (34%) | n = 993 (32%) | n = 636 (21%) | ||
| History of breathing problems | 20% | 54% | 16% | 19% | 7% | <0.001 |
| History of eczema | 14% | 27% | 19% | 7% | 9% | <0.001 |
| Wheeze at ED presentation | 63% | 76% | 100% | 57% | 0% | <0.001 |
| Cough at ED presentation | 87% | 85% | 93% | 88% | 77% | <0.001 |
| Inadequate oral intake at ED presentation | 51% | 38% | 28% | 90% | 37% | <0.001 |
| Retractions at ED presentation | <0.001 | |||||
| None | 22% | 18% | 18% | 5% | 55% | |
| Mild | 45% | 44% | 57% | 32% | 45% | |
| Severe | 33% | 38% | 25% | 62% | 0% | |
| Hospital length-of-stay | <0.001 | |||||
| <3 days | 57% | 74% | 74% | 23% | 73% | |
| 3-6 days | 33% | 20% | 26% | 53% | 22% | |
| ≥7 days | 10% | 6% | 0% | 24% | 6% | |
| RSV | 75% | <1% | 86% | 92% | 75% | <0.001 |
| Rhinovirus | 23% | 74% | 15% | 19% | 13% | <0.001 |
Abbreviations: ED, emergency department; RSV, respiratory syncytial virus.