Table 1.

Anti-dsDNA antibodies included in the different classification criteria of SLE over the years.

Classification Criteria	1982 ARA	1997 ACR	2012 SLICC	2019 EULAR/ACR
Anti-dsDNA	antibody to native DNA at abnormal titer	antibody to native DNA at abnormal titer	anti-dsDNA above laboratory reference range (except ELISA: twice above laboratory reference range)	anti-dsDNA antibodies detected by an immunoassay with demonstrated ≥90% specificity for SLE against relevant disease controls
Weight assigned to anti-dsDNA	1	1	1	6
Minimum weighted score to classify as SLE	4 (max 11)	4 (max 11)	4 (max 17)	10 (max 51)