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. 2021 Dec 29;33:102931. doi: 10.1016/j.nicl.2021.102931

Table 1.

Clinical and MRI characteristics of the studies applying structural MRI techniques.

Authors Study design Subjects Training mode Setting Disease phenotype Session duration (min) Total duration Imaging
Upper limb rehabilitation
Fan et al. (2015) CS Tot = 10 RAT PT Subacute 90 4 weeks (5 d/w) DTI
Gauthier et al. (2008) RCT Tot = 49 CIMT PT Chronic 180 10 days VBM
Lower limb rehabilitation
Yang et al. (2017) Open label Tot = 10 RAT PT Subacute 45 7 weeks (3d/w) DTI
Kim et al. (2020) RCT Tot = 11
Group 1 = 5
Group 2 = 6
RAT IP Subacute 45 4 weeks (5d/w) DTI§

RCT-randomized controlled trial; CS-case series; PT-physiotherapist supervised; IN-inpatient; CIMT-constraint induced movement therapy; RAT-robot assisted therapy; VBM -voxel based morphometry; DTI-diffusion tensor imaging;

§Only in this study there were 2 MRI follow-ups