Table 2.

Whole-brain comparisons of R2* among patients with PD-MCI and PD-CN, and HCs.

			Peak MNI coordinates
Modality	Group comparison	Cluster size (number of voxels)	X	Y	Z	Peak T-value	Anatomical region
PD-MCI vs. PD-CN
R*	PD-MCI < PD-CN	3882	−33	−9	−16	7.25	sCC cerebral peduncle, L retrolenticular part of internal capsule, L PTR, L sagittal stratum, L external capsule, L fornix, L SLF, L uncinate fasciculus, L
		993	39	−14	−12	4.73	bCC sCC SCR, R PCR, Rcingulum (cingulate gyrus) , R
		973	21	−24	34	4.21	bCC sCC SCR, R PCR, Rcingulum (cingulate gyrus) , R
PD-MCI vs. HC
R2*	PD-MCI < HC	17,378	21	−22	32	7.18	gCC bCC sCC anterior and posteriorlimb of internal capsule, R retrolenticular part of internal capsule, R, L ACR, R, L SCR, R, L PCR, R, L PTR, R, L sagittal stratum, R external capsule, Rcingulum (cingulate gyrus) , R, L cingulum (hippocampus) fornix, R SLF, R superior fronto-occipital fasciculus, R, L tapetum, R, L

HC, healthy control; PD-MCI, Parkinson’s disease with mild cognitive impairment; PD-CN, Parkinson’s disease with normal cognition; gCC, genu of the corpus callosum; bCC, body of the corpus callosum; sCC, splenium of the corpus callosum; PTR, posterior thalamic radiation; ACR, anterior corona radiata; SCR, superior corona radiata; PCR, posterior corona radiata; SLF, superior longitudinal fasciculus; R, right; L, left.