Fig. 5.

In vivo follow-up of choroid plexus injury and its association with ventricle enlargement. A MRI follow-up with T1/T2* mixed contrast FISP reveals that iron accumulation in the choroid plexus is bilateral (pairs of white arrows) and stable from 1- to 6-month post-injury. Sham-operated experimental controls had no iron in the choroid plexus (insert with black arrows). In the lesioned cerebral cortex, iron (black arrow head) surrounds the lesion cavity (white asterisk). B Chronic choroid plexus iron load at 6 months post-TBI correlated with the contralateral ventricle volume at 6 months (p < 0.01). C Greater the choroid plexus iron load at 1 month, the greater the subsequent contralateral ventricular growth from 1 to 6 months (p ≤ 0.05). Pearson correlation is displayed with linear regression line with 95% confidence intervals