Fig. 7.

Spatial learning and memory performance in the Morris water-maze test. A Latency to find the submerged platform was longer in rats with lateral fluid-percussion injury as compared to sham-operated experimental controls on all testing days. B Latency to the platform on the last trial of the 3rd training day was used as a measure of memory performance. We found that the larger the volume of the contralateral lateral ventricle, the longer the latency to the platform at 6 months post-injury (all animals r = 0.716, p < 0.001, n = 23; TBI animals only r = 0.505, p < 0.05, n = 18). Statistical significances: *p < 0.05, **p < 0.01 (Mann–Whitney at each timepoint corrected for multiple comparisons). Pearson correlation is displayed with linear regression line with 95% confidence intervals