Table 1.
Mean anatomical fiducial localization error (AFLE) with standard deviation calculated for expert raters (MA and GG) and novice raters (AT, MJ and RC)
| Fiducial | Fiducial name | Expert AFLE (mm) | Novice AFLE (mm) |
|---|---|---|---|
| 1 | AC | 0.54 ± 0.36 | 0.81 ± 0.45 |
| 2* | PC | 0.41 ± 0.75 | 0.65 ± 1.09 |
| 3 | Infracollicular sulcus | 0.92 ± 1 | 1.15 ± 0.71 |
| 4 | PMJ | 0.86 ± 1.28 | 1.03 ± 1.92 |
| 5* | Superior interpeduncular fossa | 1.60 ± 1.48 | 1.16 ± 1.23 |
| 6 | R superior LMS | 1.35 ± 1.75 | 1.44 ± 1.35 |
| 7 | L superior LMS | 1.55 ± 1.5 | 1.43 ± 1.72 |
| 8 | R inferior LMS | 1.61 ± 1.45 | 1.99 ± 1.9 |
| 9 | L inferior LMS | 1.68 ± 1.27 | 1.94 ± 1.44 |
| 10 | Culmen | 1.35 ± 0.6 | 1.86 ± 0.68 |
| 11 | Intermammillary sulcus | 0.64 ± 0.71 | 0.78 ± 0.85 |
| 12 | R MB | 0.78 ± 0.78 | 0.87 ± 0.92 |
| 13 | L MB | 0.85 ± 1.47 | 0.82 ± 1.34 |
| 14 | Pineal gland | 1.41 ± 1.35 | 1.53 ± 1.29 |
| 15* | R LV at AC | 1.32 ± 1.41 | 2.74 ± 1.45 |
| 16* | L LV at AC | 1.43 ± 1.39 | 2.93 ± 1.2 |
| 17 | R LV at PC | 1.30 ± 1.31 | 2.02 ± 1.02 |
| 18 | L LV at PC | 1.16 ± 1 | 1.65 ± 0.93 |
| 19 | Genu of CC | 0.96 ± 0.89 | 1.22 ± 1.07 |
| 20* | Splenium | 0.98 ± 1.11 | 1.47 ± 1.67 |
| 21 | R AL temporal horn | 1.39 ± 1.35 | 1.64 ± 1.6 |
| 22 | L AL temporal horn | 1.48 ± 1.51 | 2.00 ± 1.38 |
| 23 | R superior AM temporal horn | 1.45 ± 1.56 | 1.78 ± 1.55 |
| 24 | L superior AM temporal horn | 1.56 ± 2.19 | 1.94 ± 2.4 |
| 25 | R inferior AM temporal horn | 2.29 ± 2.57 | 2.85 ± 2.34 |
| 26 | L inferior AM temporal horn | 2.46 ± 1.55 | 3.01 ± 1.48 |
| 27 | R indusium griseum origin | 1.51 ± 1.87 | 2.10 ± 1.64 |
| 28 | L indusium griseum origin | 1.75 ± 1.42 | 2.04 ± 1.26 |
| 29 | R ventral occipital horn | 1.34 ± 1.37 | 1.91 ± 1.58 |
| 30 | L ventral occipital horn | 1.48 ± 2.17 | 2.24 ± 1.3 |
| 31 | R olfactory sulcal fundus | 1.73 ± 1.85 | 2.23 ± 1.25 |
| 32* | L olfactory sulcal fundus | 1.55 ± 1.34 | 2.29 ± 1.33 |
| Mean | 1.33 ± 0.79 | 1.73 ± 1.30 |
Wilcoxon rank-sum tests were obtained for each anatomical fiducial (AFID) between expert and novice raters, with a significance threshold of 0.05/32. 6 AFIDs had significantly different AFLEs obtained by novice and expert raters. All but one AFID (05) had higher AFLEs obtained by novice raters. AC, anterior commissure; AL, anterolateral; AM, anteromedial; CC, corpus callosum; IPF, interpeduncular fossa; MB, mammillary body; LMS, lateral mesencephalic sulcus; LV, lateral ventricle; PC, posterior commissure; PMJ, pontomesencephalic junction