Table 2.
The risk of bullous pemphigoid in patients with a preceding diagnosis of melanoma stratified by age, sex, and ethnicity (case–control study design)
| Subgroup | Melanoma in patients with BP n (%)a |
Melanoma in controls n (%)a |
OR (95% CI) | Univariate P value |
|---|---|---|---|---|
| All | 59 (1.5%) | 190 (1.0%) | 1.53 (1.14–2.06) | 0.004 |
| Age, years | ||||
| < 70 | 6 (0.7%) | 33 (0.7%) | 0.93 (0.39–2.23) | 0.873 |
| 71–80 | 17 (1.5%) | 51 (0.9%) | 1.69 (0.97–2.93) | 0.061 |
| ≥ 80 | 36 (1.9%) | 106 (1.2%) | 1.63 (1.11–2.38) | 0.012 |
| Sex | ||||
| Male | 29 (1.8%) | 86 (1.1%) | 1.66 (1.09–2.54) | 0.018 |
| Female | 30 (1.3%) | 104 (0.9%) | 1.43 (0.95–2.15) | 0.087 |
| Ethnicity | ||||
| Jews | 59 (1.6%) | 189 (1.0%) | 1.54 (1.15–2.07) | 0.004 |
| Arabs | 0 (0.0%) | 1 (0.1%) | NA | 0.658 |
OR odds ratio, n number, CI confidence interval
aThe prevalence of melanoma in cases when melanoma preceded BP (in cases) or preceded recruitment (in controls)
Bold: significant value