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. Author manuscript; available in PMC: 2023 Jan 1.
Published in final edited form as: Kidney Int. 2021 Nov 10;101(1):144–151. doi: 10.1016/j.kint.2021.09.032

Figure 1.

Figure 1.

Circus plot showing metabolites significantly associated with eGFR (FDR<0.05) clustered based on super pathways, with novel (outer circle), novel replicated (middle circle) and previously published associated metabolites (inner circle). Each dot is a metabolite p-value, shown as −10 log(p-value). The internal chord diagram represents the pairwise correlations among metabolites for Pearson correlation (r) >0.7 with links related to gray=two newly associated metabolite, red=previously published with newly associated metabolites, green=two previously published metabolites. Note the p-values are lower for previously published metabolites compared to newly identified metabolites.