TABLE 2.
Diagnostic Performance of Coronary CTA and CT-MPI
| Sensitivity | Specificity | PPV | NPV | Accuracy | TP | TN | FP | FN | |
|---|---|---|---|---|---|---|---|---|---|
| Per vessel | |||||||||
| Coronary CTA stenosis of ≥50% | 96 (91–100) | 72 (66–78) | 54 (46–63) | 98 (96–100) | 78 (73–83) | 71 | 155 | 60 | 3 |
| Coronary CTA stenosis of ≥70% | 45 (33–56) | 94 (91–98) | 73 (60–87) | 83 (78–88) | 82 (77–86) | 33 | 203 | 12 | 41 |
| Coronary CTA plus CT-MPI | 84a,b (75–92) | 89a,b (85–93) | 73a (63–83) | 94a,b (91–97) | 88a,b (84–92) | 62 | 192 | 23 | 12 |
| Per patient | |||||||||
| Coronary CTA stenosis of ≥50% | 94 (88–100) | 53 (39–66) | 65 (55–76) | 91 (81–100) | 73 (65–81) | 51 | 30 | 27 | 3 |
| Coronary CTA stenosis of ≥70% | 57 (44–71) | 89 (81–98) | 84 (71–96) | 69 (58–80) | 74 (66–82) | 31 | 51 | 6 | 23 |
| Coronary CTA plus CT-MPI | 89b (80–98) | 79a (68–90) | 80a (70–90) | 88b (79–97) | 84a (77–91) | 48 | 45 | 12 | 6 |
Values are % (95% CI) or n. Sensitivity, specificity, and accuracy of coronary CTA stenosis of ≥50% and ≥70% were compared to coronary CTA plus CT-MPI using the McNemar test and PPV and NPV using the weighted generalized score statistic.
a
P < 0.05 for coronary CTA stenosis ≥50%.
b
P < 0.05 for coronary CTA stenosis of ≥70%.
FN = false negative; FP = false positive; NPV = negative predictive value; PPV = positive predictive value; TN = true negative; TP = true positive; other abbreviations as in Table 1.