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. 2022 Jan 1;18(2):585–598. doi: 10.7150/ijbs.65019

Figure 4.

Figure 4

RocA increases the expressions of CCL5 and CXCL10 depending on TBK1 and STING. A, DEGs related to the cGAS-STING signaling pathway were richened. A549, H1299, H1975, and LLC cells were treated with or without 25 nM of RocA in the presence or absence of 5 µM CYT387 (B), 5 µM H-151 or 5 µM C-176 (C), or 10 µM BAY11 for 24 h, and then the expressions of CCL5 and CXCL10 were analyzed by real-time PCR. Data were pooled from three independent experiments. *, p < 0.05; **, p < 0.01; ***, p < 0.001.