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. 2022 Jan 1;18(2):491–506. doi: 10.7150/ijbs.66841

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Overexpressed LHPP restricted the growth of xenograft tumors in vivo (A) Images of the xenograft tumors from BALB/c mice induced with NC, Vector, OE-LHPP groups cells. (B) Technical roadmap of tumor formation experimental procedures in nude mice. (C) Changes in tumor weight within 30 days after injection of cells in BALB/c mice. (D) The tumors peeled from BALB/c mice are presented. (E) Tumors volume after being inoculated with different groups of SCC15 cells for 30 days. (F, G, H) Representative images of HE and LHPP IHC staining of xenografts in NC, Vector and OE-LHPP groups. (I) Representative images of PCNA IHC staining of xenografts in NC, Vector and OE-LHPP groups. **p<0.01, ***P < 0.001.