Figure 6.

Analysis of proteomic data with volcano-plot in WT and CPNS1 KO (knockout) mitochondria. (a) Volcano-plot of WT-IR vs WT-TC. (b) Volcano-plot of KO-IR vs KO-TC. (c) Volcano-plot of KO-IR vs WT-IR. The ratios of the average protein abundances in WT-IR group to the average protein abundances in WT-TC group were presented in log2() scale on the x-axis, and the p value from t-test between these 2 groups were presented in − log10() scale on the y-axis. The significant threshold for p-value was set at < 0.05 (red line). Above this threshold, the proteins with greater than twofold increased abundances in WT-IR group over WT-TC group were colored in red, and the proteins with greater than twofold decreased abundances in WT-IR group over WT-TC group were colored in green.