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. 2022 Jan 7;12:126. doi: 10.1038/s41598-021-04082-1

Table 2.

Gene expression in KRT9L3 + versus KRT9LC2 + cells: Genes upregulated in KRT9L3 + keratinocytes (interscale epidermis).

Rank Gene symbol Gene name P-value (adjusted) Average Log(e) FC Percentage (KRT9L3 + cells) Percentage (KRT9LC2 + cells)
1 KRT9L3 Keratin 9-like 3 1.50E−129 1.76 100 46
2 ENSGALG00000007127 Fatty acid desaturase 1 (FADS1) 5.13E−38 0.69 57 12
3 CBP63-K Corneous beta-protein 63 keratinocyte type 1.89E−34 2.47 63 26
4 ENSGALG00000045042 D-beta-hydroxybutyrate dehydrogenase, mito.-like 4.14E−33 0.64 63 22
5 CBP62-K Corneous beta-protein 62 keratinocyte type 8.51E−29 2.02 52 16
6 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 4.79E−27 0.48 95 82
7 KRT9L4 Keratin 9-like 4 9.55E−27 1.08 40 6
8 LGALS1 Galectin 1 2.21E−26 0.46 100 99
9 PRDX1 Peroxiredoxin 1 4.20E−26 0.54 58 21
10 S100A6 S100 calcium binding protein A6 5.43E−24 0.60 97 88
11 GPX1 Glutathione peroxidase 1 5.47E−24 0.38 100 94
12 IL13RA2 Interleukin 13 receptor subunit alpha 2 1.01E−20 0.28 28 1
13 SCCPDH Saccharopine dehydrogenase (putative) 2.76E−20 0.43 53 21
14 ENSGALG00000021451 Uncharacterized oxidoreductase-like 4.21E−20 0.39 58 25
15 ENSGALG00000045989 Trypsin II-P29-like, lincRNA 5.95E−19 0.41 49 18
16 S100A11 S100 calcium binding protein A11 2.50E−18 0.40 91 81
17 ENSGALG00000007220 Ferritin heavy chain 1 1.84E−17 0.41 56 23
18 ST13 ST13 Hsp70 interacting protein 8.37E−16 0.29 45 15
19 ACAT2 Acetyl-CoA acetyltransferase 2 9.12E−14 0.29 35 10
20 BARX2B BARX homeobox 2B 1.42E−13 0.25 20 1
21 YBX1 Y-box binding protein 1 1.84E−13 0.35 86 62
22 PPA1 Inorganic pyrophosphatase 1 6.03E−12 0.22 30 7
23 MOGAT1 Monoacylglycerol O-acyltransferase 1 5.43E−11 0.19 19 2
24 OLAH Oleoyl-ACP hydrolase 7.13E−11 0.18 19 1
25 ATP5G3 ATP synthase, mitochondrial F0 complex, subunit C3 3.76E−10 0.37 60 38
26 ANXA1 Annexin A1 4.20E−10 0.34 46 20
27 NAP1L1 Nucleosome assembly protein 1 like 1 4.79E−10 0.26 52 26
28 TKT Transketolase 9.13E−10 0.21 31 10
29 DUSP14 Dual specificity phosphatase 14 1.55E−09 0.27 41 18
30 EDQM2-EDC Epidermal differentiation protein Q motif 2, EDC 1.61E−09 0.39 35 12
31 ENSGALG00000045170 Lymphocyte antigen 6E-like 2.82E−09 0.31 20 3
32 CHCHD2 Coiled-coil-helix-coiled-coil-helix domain containing 2 3.27E−09 0.31 76 62
33 FDPS Farnesyl diphosphate synthase 5.30E−09 0.45 40 18
34 ENSGALG00000006723 Isopentenyl-diphosphate delta isomerase 1 5.48E−09 0.28 34 13
35 IL20RA Interleukin 20 receptor subunit alpha 6.03E−09 0.16 19 3
36 PPDPF Pancreatic progenitor cell diff. proliferation factor 6.45E−09 0.29 65 46
37 ENSGALG00000008439 CD36 9.64E−09 0.20 23 5
38 HOMER2 Homer scaffold protein 2 2.80E−08 0.19 28 8
39 ACLY ATP citrate lyase 3.09E−08 0.26 38 17
40 ATP5G1 ATP synthase, H + transporting, mito. F0 compl. sub. C1 4.27E−08 0.29 57 35
41 HACD3 3-hydroxyacyl-CoA dehydratase 3 5.08E−08 0.20 32 12
43 EDQM1-EDC Epidermal differentiation protein Q motif 1, EDC 8.39E−08 0.47 39 18
45 KRT9L1 Keratin 9-like 1 1.14E−07 0.17 15 1
52 HSD17B12 Hydroxysteroid 17-beta dehydrogenase 12 4.27E−07 0.21 35 15
54 ELOVL4 ELOVL fatty acid elongase 4 6.89E−07 0.41 76 62
74 FASN Fatty acid synthase 8.33E−05 0.17 26 10
75 ENSGALG00000027494 Serine palmitoyltransferase small subunit B (SPTSSB) 1.05E−04 0.19 40 21
79 LOR1-EDC Loricrin 1, EDC 2.53 E−04 0.17 10 1
80 ENSGALG00000045194 Lipase member M-like 2 2.53 E−04 0.10 10 1
92 ENSGALG00000044962 Arylacetamide deacetylase-like 4-like (AADAC4L) 2.55E−03 0.21 21 8