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. 2022 Jan 7;12:269. doi: 10.1038/s41598-021-04334-0

Table 3.

Parameter values for the circadian clock of Drosophila, taken from the work of Tyson et al.67. Cm and Cp are characteristic concentrations for mRNA and protein, respectively.

Name Value Units Description
vm 1.0 Cm h-1 Maximum rate of mRNA synthesis
km 0.1 h-1 mRNA degradation rate constant
vp 0.5 Cp Cm-1 h-1 mRNA rate constant
kp1 10 Cp h-1 Vmax of monomer phosphorylation
kp2 0.03 Cp h-1 Vmax of dimer phosphorylation
kp3 0.1 h-1 Proteolysis rate constant caused by CRY activation
Keq 200 Cp-1 Dimerization equilibrium constant
Pcrit 0.1 Cp Dimer concentration at the half-maximum transcription rate
Jp 0.05 Cp Michaelis constant for protein kinase (DBT)