Table 3.

Representative pigmentation-related genes differentially expressed in each compared groups.

Gene name	Description	YR1d-vs-YR45d		YR1d-vs-YR90d		YR45d-vs-YR90d
		Log2 (FC)	FDR	Log2 (FC)	FDR	Log2 (FC)	FDR
Pteridine synthesis
GCH1	GTP cyclohydrolase 1	2.27	1.18E − 68	3.17	4.60E − 165	0.89	6.31E − 12
SLC2A11	Solute carrier family 2 member 11	2.44	2.78E − 48	3.30	4.08E − 110	0.86	6.15E − 09
CSF1R1	Colony-stimulating factor 1 receptor 1	2.75	5.38E − 92	3.48	4.77E − 123	0.73	1.12E − 12
PTS	Pyruvoyl tetrahydrobiopterin synthase	1.16	1.67E − 14	2.00	1.76E − 45	0.83	2.11E − 07
QDPR	Dihydropteridine reductase	2.14	3.37E − 70	1.94	8.60E − 33	− 0.21	0.78
SOX5	Transcription factor sox-5	− 1.87	3.34E − 06	− 2.40	4.28E − 08	− 0.52	0.54
PAX3	Paired box protein pax-3	− 3.97	3.10E − 32	− 5.08	3.10E − 23	− 1.39	0.32
Carotenoid synthesis
SCARB1	Scavenger receptor class B member 1	2.07	2.27E − 16	2.96	6.16E − 32	0.89	2.82E − 08
DGAT2	Diacylglycerol O-acyltransferase 2	3.50	6.98E − 52	6.78	9.27E − 152	3.29	9.50E − 55
PNPLA2	Patatin-like phospholipase protein 2	3.68	6.77E − 11	4.42	2.26E − 15	0.74	0.02
APOD	Apolipoprotein D	5.58	0.00	5.68	0.00	0.10	0.16
BCO2	Beta,beta-carotene 9′,10′-oxygenase	1.69	0.01	2.35	8.21 × 10−4	− 1.04	0.31
Melanin synthesis
TYR	Tyrosinase precursor	1.84	1.14E − 62	1.86	1.43E − 56	0.03	0.43
TYRP1	Tyrosinase-related protein 1	1.86	1.40E − 89	2.72	3.67E − 121	0.86	4.78E − 12
DCT	l-Dopachrome tautomerase	3.31	2.04E − 95	4.17	1.69E − 136	0.86	7.76E − 14
MITF	Microphthalmia transcription factor	1.62	4.82E − 14	1.99	4.38E − 34	0.36	0.09
MC1R	Melanocortin 1 receptor	2.25	7.36E − 35	1.70	3.87E − 12	− 0.55	0.10
PMEL	Melanocyte protein	− 6.02	5.21E − 122	− 6.67	4.13E − 93	− 0.64	0.61
SLC45A2	Solute carrier family 45 member 2	1.80	2.58E − 37	2.23	2.97E − 49	0.43	3.17 × 10−3
OCA2	P protein	2.10	6.43E − 37	2.96	7.23E − 73	0.86	1.50E − 11
GPR143	G-protein coupled receptor 143	2.03	2.05E − 29	2.91	2.56E − 55	0.88	2.95E − 08
KITA	Stem cell growth factor receptor kita	3.22	3.23E − 65	2.60	2.16E − 27	− 0.62	0.02
SLC7A11	Cystine/glutamate transporter	− 3.92	2.16E − 14	− 6.60	5.69E − 11	− 2.67	0.17