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. 2022 Jan 7;12:134. doi: 10.1038/s41598-021-04075-0

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Adjusted drug retention by age and sex. Adjusted drug retention between young (< 65 years), aged (65–74 years), and very old (≥ 75 years) groups, due to (a) lack of effectiveness and (b) toxic adverse events, and adjusted drug retention between male and female, due to (c) lack of effectiveness and (d) toxic adverse events.