Table 1.

Demographic and clinical characteristics between with and without hypoalbuminemia patients underwent craniotomy for brain tumor.

Variables	Non-hypoalbuminemia N = 39 (10.5%)	Hypoalbuminemia N = 333 (89.5%)	P value
Age (years, mean ± SD)	46 ± 13	48 ± 13	0.311
Sex [M, n (%)]	20 (51.3)	141 (42.3)	0.286
BMI	24.9 ± 2.7	23.4 ± 3.3	0.010
Medical history [n (%)]
Hypertension	5 (12.8)	57 (17.1)	0.496
Diabetes	2 (5.1)	12 (3.6)	0.636
Coronary heart disease	2 (5.1)	5 (1.5)	0.115
Viral hepatitis	1 (2.6)	11 (3.3)	0.805
History of stroke	1 (2.6)	3 (0.9)	0.341
Lifestyle factors [n (%)]
Smoking	12 (30.8)	82 (24.6)	0.403
Drinking	4 (10.3)	36 (10.8)	0.916
Pathological classification [n (%)]
Meningiomas	13 (33.3)	131 (39.3)	0.288
Gliomas	9 (23.1)	111 (33.3)
Acoustic neuromas	3 (7.7)	21 (6.3)
Metastatic tumors	3 (7.7)	15 (4.5)
Others	11 (28.2)	55 (16.5)
Intraoperative blood loss [(mL, median (IQR)]	200 (200–300)	300 (300–500)	< 0.001
Intraoperative total input [(mL, median (IQR)]	2200 (1813–2688)	2850 (2300–3500)	< 0.001
Intraoperative total urine output [(mL, median (IQR)]	1775 (1400–2500)	2600 (2015–3350)	< 0.001
Operation time [(h, median (IQR)]	3.8 (2.7–5.0)	5.0 (4.0–6.0)	< 0.001
NICU time [(days, median (IQR)]	4 (3–5)	4 (3–5)	0.068
Hospitalization time [(days, median (IQR)]	21 (17–28)	21 (18–28)	0.524
Postoperative complications [n (%)]
Pneumonia	–	18 (5.4)	0.137
Pulmonary imaging abnormalities	9 (23.1)	137 (41.1)	0.029
Epilepsy	3 (7.7)	10 (3.0)	0.131
Incision infection	–	3 (0.9)	0.552
Respiratory failure	–	11 (3.3)	0.249
Renal failure	–	3 (0.9)	0.552
Hydrocephalus	–	3 (0.9)	0.552
Deep vein thrombosis	–	2 (0.6)	0.627

BMI Body Mass Index, NICU Neurological Intensive Care Unit, SD standard deviation, IQR interquartile range.