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. 2022 Jan 7;12:193. doi: 10.1038/s41598-021-03272-1

Table 2.

Changes in liver fibrosis markers after DAA treatment.

Baseline 48 W 96 W 144 W p-value
Liver stiffness, kPa 19.37 ± 12.86 13.88 ± 9.13 11.70 ± 8.23 10.09 ± 6.23  < 0.001
FIB-4 6.29 ± 4.67 3.25 ± 2.14 2.87 ± 1.59 2.89 ± 1.70  < 0.001
APRI 1.36 ± 0.86 0.66 ± 0.62 0.50 ± 0.29 0.43 ± 0.21  < 0.001

K-paired sample Friedman tests were used as normality tests were not satisfied.

DAA, direct antiviral agent; FIB-4, fibrosis-4; APRI, Aspartate transaminase to platelet ratio index; W, week.