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. 2022 Jan 7;12:193. doi: 10.1038/s41598-021-03272-1

Table 3.

Changes in liver stiffness before and after propensity score matching (PS1).

Before PS matching After PS matching
Outcome IFN (n = 92) DAA (n = 82) p value IFN (n = 42) DAA (n = 42) p value
Change of LS value at 48 W, kPa (%) 0.62 ± 1.39 (8%) 5.78 ± 7.69 (27%)  < 0.0001 0.75 ± 1.68 (9%) 5.74 ± 8.53 (29%)  < 0.0001
Change of LS value at 96 W, kPa (%) 1.46 ± 2.79 (15%) 7.92 ± 8.28 (37%)  < 0.0001 1.55 ± 2.85 (17%) 7.11 ± 8.44 (39%) 0.0001
Significant regression at 48 W 5 (5.5) 40 (48.8)  < 0.0001 3 (7.1) 23 (54.8)  < 0.0001
Significant regression at 96 W 12 (13.2) 52 (63.4)  < 0.0001 5 (15.6) 27 (64.3)  < 0.0001

Changes of LS value are described as subtracted change from baseline LS (percentage change).

Significant regression was defined as more than 30% reduction of liver stiffness from baseline.

PS, propensity matching; IFN, interferon; DAA, direct antiviral agents; LS, liver stiffness; W, week.