Table 2.
EORTC QLQ-C30 characteristics of 2871 prostate cancer patients treated with robot-assisted radical prostatectomy at the Prostate Cancer Center Northwest, Gronau, Germany between 2006 and 2018 stratified according to the CAPRA-S risk group and fulfillment the pentafecta criteria.
| Value | All patients (n = 2871) | CAPRA-S low risk group (n = 1514) | CAPRA-S intermediate risk group (n = 925) | CAPRA-S high risk group (n = 432) | p-value | Pentafecta group (n = 1469) | Nonpentafecta group (n = 1402) | p-value | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Preoperative Global Quality of Life (QL), mean (SD) | 75.4 | 19.2 | 75.7 | 19.4 | 75.1 | 18.9 | 75.2 | 19.4 | 0.7a | 75.6 | 19.7 | 75.2 | 18.7 | 0.6 |
| Preoperative EORTC QLQ-C30 Summary Score, mean (SD) | 91.0 | 9.1 | 91.0 | 9.2 | 90.9 | 8.9 | 91.2 | 9.2 | 0.8a | 91.3 | 9.0 | 90.7 | 9.3 | 0.08 |
| Global Quality of Life (QL) at 24 months after surgery, mean (SD) | 77.5 | 19.5 | 79.3 | 19.3 | 76.5 | 19.1 | 73.7 | 20.7 | < 0.001a | 80.8 | 18.3 | 74.1 | 20.2 | < 0.001 |
| EORTC QLQ-C30 Summary Score at 24 months after surgery, mean (SD) | 89.3 | 11.9 | 90.2 | 11.5 | 88.8 | 11.6 | 87.6 | 13.4 | < 0.001a | 91.2 | 10.3 | 87.4 | 13.1 | < 0.001 |
| Global Quality of Life (QL) change at 24 months after surgery, n (%) | ||||||||||||||
| Major improvement | 378 | 13% | 207 | 14% | 115 | 12% | 56 | 13% | < 0.001a | 224 | 15% | 154 | 11% | < 0.001 |
| Moderate improvement | 441 | 15% | 259 | 17% | 130 | 14% | 52 | 12% | 257 | 17% | 184 | 13% | ||
| Minor improvement | 342 | 12% | 199 | 13% | 112 | 12% | 31 | 7.2% | 206 | 14% | 136 | 10% | ||
| Stable | 834 | 29% | 451 | 30% | 271 | 29% | 112 | 26% | 442 | 30% | 392 | 28% | ||
| Minor deterioration | 274 | 10% | 126 | 8.3% | 94 | 10% | 54 | 13% | 111 | 7.6% | 163 | 12% | ||
| Moderate deterioration | 327 | 11% | 147 | 10% | 114 | 12% | 66 | 15% | 140 | 10% | 187 | 13% | ||
| Major deterioration | 275 | 10% | 125 | 8.3% | 89 | 10% | 61 | 14% | 89 | 6.1% | 186 | 13% | ||
| EORTC QLQ-C30 Summary Score change at 24 months after surgery, n (%) | ||||||||||||||
| Major improvement | 41 | 1.4% | 22 | 1.5% | 10 | 1.1% | 9 | 2.1% | < 0.001a | 25 | 1.7% | 16 | 1.1% | < 0.001 |
| Moderate improvement | 167 | 5.8% | 98 | 6.5% | 47 | 5.1% | 22 | 5.1% | 93 | 6.3% | 74 | 5.3% | ||
| Minor improvement | 307 | 11% | 193 | 13% | 82 | 8.9% | 32 | 7.4% | 181 | 12% | 126 | 9.0% | ||
| Stable | 1579 | 55% | 848 | 56% | 510 | 55% | 221 | 51% | 877 | 60% | 702 | 50% | ||
| Minor deterioration | 350 | 12% | 163 | 11% | 127 | 14% | 60 | 14% | 140 | 10% | 210 | 15% | ||
| Moderate deterioration | 293 | 10% | 136 | 9.0% | 103 | 11% | 54 | 13% | 112 | 7.6% | 181 | 13% | ||
| Major deterioration | 134 | 4.7% | 54 | 3.6% | 46 | 5.0% | 34 | 7.9% | 41 | 2.8% | 93 | 6.6% | ||
Significant values are in italics.
CAPRA-S the postsurgical Cancer of the Prostate Risk Assessment score, EORTC QLQ-C30 European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30, SD standard deviation, QoL quality of life.
aCAPRA-S low risk vs. CAPRA-S high risk.