Table 4. Factors associated with HIV drug resistance among newly diagnosed HIV individuals in 2015 and 2018, China.
Factors | Total | TDR (%) | OR (95% CI) | P | AOR (95% CI) | P |
Abbreviations: HIV=human immunodeficiency virus; TDR=transmitted drug resistance; OR=odds ratio; CI=confidence interval; AOR=adjusted odds ratio; HET=heterosexual; MSM=men who have sex with men; IDU=injecting drug users. | ||||||
Total | 8,980 | 367 (4.1) | ||||
Age (years) | ||||||
16–25 | 2,230 | 78 (3.5) | 1.00 | 1.00 | ||
26–49 | 5,099 | 209 (4.1) | 1.24 (0.95–1.61) | 0.12 | 1.21 (0.93–1.58) | 0.16 |
≥50 | 1,538 | 72 (4.7) | 1.41 (1.02–1.95) | 0.04 | 1.39 (1.00–1.94) | 0.05 |
Unknown | 113 | 8 (7.1) | 2.11 (1.00–4.48) | 0.05 | 2.05 (0.96–4.37) | 0.06 |
Sex | ||||||
Male | 7,358 | 299 (4.1) | 1.00 | |||
Female | 1,557 | 65 (4.2) | 1.03 (0.78–1.35) | 0.84 | ||
Unknown | 65 | 3 (4.6) | 1.12 (0.35–3.60) | 0.84 | ||
Education | ||||||
Primary school | 2,331 | 90 (3.9) | 1.00 | |||
Junior high school | 2,617 | 120 (4.6) | 1.20 (0.91–1.58) | 0.21 | ||
Senior high school or above | 3,646 | 147 (4.0) | 1.05 (0.80–1.37) | 0.74 | ||
Unknown | 386 | 10 (2.6) | 0.66 (0.34–1.28) | 0.22 | ||
Route of HIV transmission | ||||||
HET | 4,714 | 201 (4.3) | 1.00 | |||
MSM | 3,761 | 140 (3.7) | 0.87 (0.70–1.08) | 0.21 | ||
IDU | 168 | 11 (6.5) | 1.57 (0.84–2.95) | 0.16 | ||
Others | 337 | 15 (4.5) | 1.04 (0.61–1.78) | 0.89 | ||
Subtype | ||||||
CRF01_AE | 3,413 | 135 (4.0) | 1.00 | 1.00 | ||
CRF07_BC | 3,371 | 107 (3.2) | 1.26 (0.97–1.63) | 0.08 | 1.25 (0.97–1.62) | 0.09 |
CRF08_BC | 802 | 37 (4.6) | 1.48 (1.01–2.16) | 0.05 | 1.51 (1.03–2.23) | 0.04 |
CRF55_01B | 278 | 34 (12.2) | 4.25 (2.83–6.39) | <0.001 | 4.17 (2.77–6.27) | <0.001 |
B | 444 | 19 (4.3) | 1.36 (0.83–2.25) | 0.22 | 1.36 (0.83–2.24) | 0.23 |
Others | 672 | 35 (5.2) | 1.67 (1.13–2.47) | 0.01 | 1.69 (1.14–2.49) | 0.01 |
Year |
|
|||||
2015 | 4,704 | 178 (3.8) | 1.00 | |||
2018 | 4,276 | 189 (4.4) | 1.18 (0.95–1.45) | 0.13 |