Table 2. Effect of adjuvant ATRA on HepG2 tumor formatting rate after second transplantation.
Variables | Amount of tumor [n/N* (%)] | P** for ATRA+IRFA | ||||
Control | ATRA | IRFA+ATRA | vs. Control | vs. ATRA | ||
ATRA, all-trans retinoic acid; IRFA, insufficient radiofrequency ablation. *, n: the actual number of tumors formed; N: the number of transplanted tumors. **, Fisher’s exact test was used to analyze the difference in tumor formatting rate after the second tumor formation rate between different groups. | ||||||
Day 3 | 4/12 (33.3) | 0/12 (0) | 0/12 (0) | 0.047 | − | |
Day 7 | 7/12 (58.3) | 2/12 (16.7) | 1/12 (8.3) | 0.027 | 1 | |
Day 12 | 10/12 (83.3) | 4/12 (33.3) | 3/12 (25.0) | 0.012 | 1 | |
Diameter at end-point ( ) (mm) | 13.8±1.2 | 9.2±0.5 | 6.3±0.5 | 0.007 | 0.032 |