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. 2022 Jan 7;5(1):e2142210. doi: 10.1001/jamanetworkopen.2021.42210

Table 1. Demographic and Clinical Characteristics According to Vaccine Risk Category (Nā€‰=ā€‰1917).

Characteristic No. (%) P value No. (%) P value
Total participants SARS-CoV-2 reinfection Unvaccinated Partially Fully
No. 1917 116a 472 356 1089
Age, y
<25 157 (8.2) 15 (12.9) .08 53 (11.2) 32 (9.0) 72 (6.6) <.001
25-44 1228 (64.1) 76 (65.5) 335 (71.0) 233 (65.4) 660 (60.6)
ā‰„45 532 (27.8) 25 (21.6) 84 (17.8) 91 (25.6) 357 (32.8)
Sex
Male 1107 (57.7) 62 (53.5) .33 247 (52.3) 192 (53.9) 668 (61.3) .001
Female 810 (42.3) 54 (46.5) 225 (47.7) 164 (46.1) 421(38.7)
Type of HCW
Student, administrative and/or clerical staff 182 (9.5) 8 (6.9) .02 49 (10.4) 44 (12.4) 89 (8.2) <.001
Faculty, scientist, research staff 151 (7.9) 7 (6.0) 34 (7.2) 28 (7.9) 89 (8.2)
Nursing staff 638 (33.3) 53 (45.7) 193 (40.9) 135 (37.9) 310 (28.5)
Junior or senior resident 183 (9.6) 14 (12.1) 27 (5.7) 43 (12.1) 113 (10.4)
Paramedical or support staff 763 (39.8) 34 (29.3) 169 (35.8) 106 (29.8) 488 (44.8)
BMI
<18.5 47 (2.4) 2 (1.7) .60 13 (2.8) 12 (3.4) 22 (2.0) .23
18.5-24.9 917 (47.8) 61 (52.6) 236 (50.0) 178 (50.0) 503 (46.2)
25.0-29.9 745 (38.9) 39 (33.6) 168 (35.6) 136 (38.2) 441 (40.5)
ā‰„30 208 (10.9) 14 (12.1) 55 (11.7) 30 (8.4 123 (11.3)
Comorbidityb b426 (22.2) 33 (28.5) .09 110 (23.3) 91 (25.6) 225 (20.7) .13
First episode COVID-19 symptom status
Asymptomatic 279 (14.6) 15 (12.9) .61 82 (17.4) 50 (14.0) 147 (13.5) .13
Symptomatic 1638 (85.4) 101 (87.1) 390 (82.6) 306 (86.0) 942 (86.5)

Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); HCW, health care worker.

a

Of 124 reinfection events, 116 were included in the analysis because 5 were reinfected before vaccine rollout and 3 received a different vaccine.

b

Defined as diabetes; hypertension; chronic heart, lung, or kidney disease; cancer; hypothyroidism; or other self-reported chronic condition.