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. 2022 Jan 7;8(4):612–617. doi: 10.1001/jamaoncol.2021.7777

Figure. Humoral Immune Response After 2 or 3 Doses of BNT162b2 Vaccine.

Figure.

Anti-S immunoglobulin G (IgG) titer: horizontal dotted line indicates the cutoff for positivity (1000 arbitrary units [AU]/mL) at the first (V1), second (V2), and third (V3) doses of BNT162b2 vaccine. A, Humoral immune response after 2 doses of vaccine: orange lines indicate the antibody titers of patients with an immune response greater than 1000 AU/mL at 3 months after the second dose. Blue lines indicate the antibody titer of patients who lowered their immune response at 3 months (n = 64). B, Humoral immune response after 3 doses of vaccine: orange lines indicate the antibody titers of patients with a strong immune response greater than 1000 AU/mL at 1 month after a third dose of mRNA vaccine (n = 36). Blue lines indicate the antibody titer of patients with a persistent weak immune response less than 1000 AU/mL at 1 month after a third dose of mRNA vaccine. M1 indicates first month; M3, third month; V1, first dose of BNT162b2 vaccine; V2, second dose of BNT162b2 vaccine; V3, third dose of BNT162b2 vaccine.