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. Author manuscript; available in PMC: 2023 Jan 1.
Published in final edited form as: Lancet Oncol. 2021 Dec 9;23(1):172–184. doi: 10.1016/S1470-2045(21)00582-9

Figure 2:

Figure 2:

Amino acid variation at HLA-A position 161 and association with overall survival after ICI initiation in the discovery cohort (MSK-IMPACT n=1166). Panel A shows the −log10 p-value (unadjusted) for association at each amino acid site in HLA-A (red circles), HLA-B (green circles) and HLA-C (blue circles). HLA-A position 161 is marked. Panel B shows the −log10 p-value for association at HLA-A residues after conditioning on HLA-A position 161.