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. 2022 Jan 7;22:9. doi: 10.1186/s12874-021-01491-8

Table 2.

Average variable selection performance averaged across 100 simulated datasets with standard deviations in brackets

Individual Group
Method MCC TPR TNR MCC TPR TNR
Sim 1 SMT 0.29 (0.36) 0.22 (0.27) 1.00 (0.00) 0.41 (0.49) 0.41 (0.49) 1.00 (0.00)
GMT 0.10 (0.14) 0.36 (0.48) 0.91 (0.11) 0.35 (0.49) 0.36 (0.48) 0.99 (0.05)
SGMT 0.47 (0.39) 0.41 (0.37) 1.00 (0.00) 0.60 (0.49) 0.63 (0.49) 0.97 (0.09)
ASSET 0.21 (0.34) 0.16 (0.26) 1.00 (0.00) 0.28 (0.45) 0.28 (0.45) 1.00 (0.00)
GPA 0.03 (0.12) 0.09 (0.18) 0.93 (0.17) 0.04 (0.18) 0.21 (0.41) 0.83 (0.37)
SGST 0.09 (0.21) 0.05 (0.12) 1 (0.00) 0.17 (0.38) 0.17 (0.38) 1 (0.03)
Sim 2 SMT 0.55 (0.15) 0.34 (0.16) 1.00 (0.00) 0.88 (0.20) 0.84 (0.25) 0.99 (0.03)
GMT 0.34 (0.08) 0.80 (0.27) 0.83 (0.06) 0.85 (0.21) 0.80 (0.27) 1.00 (0.02)
SGMT 0.72 (0.14) 0.56 (0.20) 1.00 (0.00) 0.95 (0.11) 0.95 (0.15) 0.99 (0.04)
ASSET 0.46 (0.19) 0.26 (0.15) 1.00 (0.00) 0.74 (0.30) 0.70 (0.33) 0.99 (0.04)
GPA 0.22 (0.2) 0.11 (0.12) 0.99 (0.07) 0.43 (0.39) 0.39 (0.37) 0.98 (0.14)
SGST 0.01 (0.05) 0.00 (0.02) 1 (0.00) 0.03 (0.13) 0.02 (0.1) 1.00 (0.00)
Sim 3 SMT 0.46 (0.08) 0.24 (0.08) 1.00 (0.00) 0.91 (0.12) 0.89 (0.16) 0.99 (0.03)
GMT 0.57 (0.03) 0.98 (0.06) 0.84 (0.01) 0.99 (0.05) 0.98 (0.06) 1.00 (0.01)
SGMT 0.73 (0.09) 0.59 (0.13) 1.00 (0.00) 0.97 (0.07) 0.99 (0.04) 0.99 (0.03)
ASSET 0.33 (0.11) 0.14 (0.08) 1.00 (0.00) 0.77 (0.20) 0.71 (0.26) 0.99 (0.04)
GPA 0.23 (0.09) 0.07 (0.04) 1.00 (0.00) 0.61 (0.23) 0.49 (0.26) 1.00 (0.01)
SGST 0.00 (0.00) 0.00 (0.00) 1 (0.00) 0.00 (0.00) 0.00 (0.00) 1.00 (0.00)
Sim 4 SMT 0.21 (0.05) 0.06 (0.02) 1.00 (0.00) 0.70 (0.15) 0.61 (0.17) 0.99 (0.02)
GMT 0.86 (0.02) 1.00 (0.03) 0.94 (0.00) 1.00 (0.02) 1.00 (0.03) 1.00 (0.00)
SGMT 0.56 (0.04) 0.38 (0.04) 1.00 (0.00) 0.99 (0.02) 1.00 (0.02) 1.00 (0.01)
ASSET 0.13 (0.08) 0.03 (0.03) 1.00 (0.00) 0.46 (0.25) 0.34 (0.24) 0.99 (0.02)
GPA 0.11 (0.05) 0.02 (0.01) 1.00 (0.00) 0.43 (0.21) 0.28 (0.18) 1.00 (0.01)
SGST 0.00 (0.00) 0.00 (0.00) 1.00 (0.00) 0.00 (0.00) 0.00 (0.00) 1.00 (0.00)

Measures of performance are based on variable (pleiotropic) effect recovery and group effect recovery