Table 2.
Characteristics of patients presenting with cutaneous symptoms.
| n (%) | |
|---|---|
| Total | 887 (69.8) |
| Urticaria, without angioedema1 | 427 (48.1) |
| Idiopathic | 327 (76.6) |
| Drug | 87 (20.4) |
| Antibiotics | 27 (6.3) |
| NSAIDs | 25 (5.9) |
| Others 2 | 35 (8.2) |
| Food | 12 (2.8) |
| Venom | 1 (0.2) |
| Urticaria, with angioedema1 | 73 (8.2) |
| Idiopathic | 48 (65.8) |
| Drug | 20 (27.4) |
| Antibiotics | 13 (17.8) |
| NSAIDs | 5 (6.8) |
| Others | 2 (2.8) |
| Food | 3 (4.1) |
| Venom | 2 (2.7) |
| Angioedema, without urticaria3 | 58 (6.5) |
| ACE inhibitors4 | 35 (60.4) |
| Idiopathic | 9 (15.5) |
| NSAIDs | 8 (13.9) |
| Other drugs | 3 (5.1) |
| Food | 1 (1.7) |
| Venom | 1 (1.7) |
| Acquired | 1 (1.7) |
| Xerosis | 137 (15.4) |
| Systemic diseases5 | 89 (10) |
| Allergic contact dermatitis6 | 39 (4.5) |
| Atopic dermatitis7 | 13 (1.5) |
| Other skin diseases8 | 51 (5.8) |
NSAIDs: Nonsteroidal antiinflammatory drugs, ACE: Angiotensin converting enzyme.1 Sex, female (n = 295, 59%), male (n = 205, 41%), atopy (n = 82, 16.4%), comorbidity (n = 398, 79.6%).2 Cardiovascular drugs (mainly ACE inhibitors and beta-blockers) (n = 8), chemotherapeutics (n = 8), allopurinol (n = 5), local anesthetics (n = 4), contrast agents (n = 3), proton pump inhibitors (n = 2), insulin (n = 2), methimazole (n = 1), pregabalin (n = 1), infliximab (n =1)3 Sex, female (n = 32, 55%), male (n = 26, 45%), atopy (n = 82, 16.4%), comorbidity (n = 12, 21%).4 ACE inhibitor-induced angioedema; 4.7% (n = 35/738). Sex, female (n = 20, 57%), male (n = 15, 43%), atopy (n = 7, 35%), comorbidity (n = 35, 100%).5 Systemic diseases; liver diseases, kidney diseases, hematologic diseases, endocrine disorders, neurologic diseases, paraneoplasic pruritus, infectious diseases.6 Ten patients who developed gingivitis and stomatitis > 24 h after dental prosthesis application were accepted as contact allergy to dental metals. Sex, female (n = 20, 51%), male (n = 19, 49%), atopy (n = 3, 7.7%), comorbidity (n = 29, 74%).7 Sex, male: 77% (n = 10), female: 23% (n = 3), atopy (n = 4, 31%), comorbidity (n = 11, 85%).8 Other skin diseases; all skin diseases other than the above diagnoses (most common scabies and bullous pemphigoid).