Table 3.
Treatments and Complications of the patients.
| 28-day status | ||||
|---|---|---|---|---|
| All cases (n=249) | Recovered group (n=80) | Deceased group (n=169) | P Value | |
| Treatment | ||||
| Favipiravir | 239 (96.0) | 80 (100.0) | 159 (94.1) | 0.033 |
| Hydroxychloroquine | 54 (21.7) | 16 (20.0) | 38 (22.5) | 0.74 |
| LMWH | 237 (95.2) | 77 (96.3) | 160 (94.7) | 0.76 |
| ASA | 193 (77.5) | 60 (75.0) | 133 (78.7) | 0.52 |
| Dipyridamole | 152 (61.0) | 42 (52.5) | 110 (65.1) | 0.07 |
| Corticosteroidsa | 195 (78.3) | 61 (76.3) | 134 (79.3) | 0.62 |
| Pulse corticosteroidb | 101 (40.6) | 29 (36.3) | 72 (42.6) | 0.41 |
| Tocilizumab | 25 (10.0) | 10 (12.5) | 15 (8.9) | 0.38 |
| Convalescent plasma | 70 (28.1) | 28 (35.0) | 42 (24.9) | 1.00 |
| Use of vasopressorc | 165 (66.3) | 22 (27.5) | 143 (84.6) | < 0.001 |
| RRT | 65 (26.1) | 7 (8.8) | 58 (34.3) | < 0.001 |
| Respiratory Support | ||||
| COT | 20 (8.0) | 18 (22.5) | 2 (1.2) | < 0.001 |
| HFNC | 90 (36.1) | 42 (52.5) | 48 (28.4) | < 0.001 |
| NIMV | 43 (17.3) | 12 (15.0) | 31 (18.3) | 0.52 |
| IMV | 192 (77.1) | 27 (33.8) | 165 (97.6) | < 0.001 |
| ECMO | 3 (1.2) | 0 (0.0) | 3 (1.8) | 0.23 |
| Complications | ||||
| Sepsis/septic shock | 166 (66.7) | 18 (22.5) | 148 (87.6) | < 0.001 |
| AKI | 139 (55.8) | 14 (17.5) | 125 (74.0) | < 0.001 |
| VAP | 118 (47.4) | 16 (20.0) | 102 (60.4) | < 0.001 |
| Acute cardiac injury | 60 (24.1) | 6 (7.5) | 54 (32.0) | < 0.001 |
| New-onset arrhythmia | 50 (20.1) | 10 (12.5) | 40 (23.7) | 0.043 |
| CPR | 9 (3.6) | 2 (2.5) | 7 (4.1) | 0.72 |
| PTE | 5 (2.0) | 3 (3.8) | 2 (1.2) | 0.33 |
All values are expressed as numbers (percentages) or median (interquartile range).Abbreviations: LMWH, low molecular weight heparin; ASA, acetylsalicylic acid; RRT, renal replacement therapy; COT, conventional oxygen therapy; HFNC, high flow nasal cannula; NIMV, noninvasive mechanical ventilation; IMV, invasive mechanical ventilation; ECMO, extracorporeal membrane oxygenation; AKI, acute kidney injury; VAP, ventilator-associated pneumonia; CPR, cardiopulmonary resuscitation; PTE, pulmonary thromboembolism.a Intravenous methylprednisolone 0.5–1 mg/kg/day.b Intravenous methylprednisolone > 250 mg/day.c