Tissue sections from DMBA-administered female SENCAR mice that received a control treatment (corn oil, CAS, or PIS) or an experimental treatment (2HF, RAS, Rab, or a combination of 2HF+RAS+Rab) were used for H&E staining. Hemorrhagic areas involving the liver, duodenum, spleen, kidney, bone marrow, mammary gland, brain, lung, and heart tissues were observed in the corn oil-, CAS-, and PIS-treated mice whereas tissues from 2HF-, RAS-, Rab-, and combination-treated mice were histologically normal. Representative images at x400 magnification are shown. 2HF, 2'-hydroxyflavanone-treated; CAS, scrambled antisense-treated; RAS, RLIP antisense-treated; PIS, preimmune serum-treated; Rab, RLIP antibody-treated.