Table 2.
Demographics and clinical characteristics of matched group (A) of SARS-CoV-2-positive patients with matched controls
| Cases SARS-CoV-2 positive N = 41,757 |
Controls not SARS-CoV-2 positive N = 417,570 |
p value | |
|---|---|---|---|
| Female (%) | 26,508 (63.5%) | 265,080 (63.5%) | 1.000 |
| Age, median [IQR] | 46 [31–62] | 46 [31–62] | 1.000 |
| Socio Economic Status (%) | |||
| Missing | 46 (0.1%) | 460 (0.1%) | 1.000 |
| Low | 20,222 (48.4%) | 202,220 (48.4%) | 1.000 |
| Medium | 15,335 (36.7%) | 153,350 (36.7%) | 1.000 |
| High | 6154 (14.7%) | 61,540 (14.7%) | 1.000 |
| Ethnic group (%) | |||
| General | 23,163 (55.5%) | 271,787 (65.1%) | < 0.001 |
| Ultra-Orthodox | 7012 (16.8%) | 41,195 (9.9%) | < 0.001 |
| Arab Population | 11,582 (27.7%) | 104,588 (25.0%) | < 0.001 |
| Vitamin D level last measured, median [IQR] | 47.7 [31.3, 65.1] | 51.0 [33.7, 68.3] | < 0.001 |
| Range (%) | |||
| < 30 nmol/L | 9740 (23.3%) | 85,383 (20.4%) | < 0.001 |
| 30–50 nmol/L | 12,735 (30.5%) | 117,319 (28.1%) | < 0.001 |
| 50–75 nmol/L | 13,130 (31.4%) | 141,058 (33.8%) | < 0.001 |
| > 75 nmol/L | 6152 (14.7%) | 73,810 (17.7%) | < 0.001 |
| BMI, median [IQR] | 26.6 [22.9–30.9] | 25.7 [22.3–29.8] | |
| < 25 kg/m2 | 16,298 (39.0%) | 187,150 (44.8%) | < 0.001 |
| 25–30 kg/m2 | 13,060 (31.3%) | 128,970 (30.9%) | < 0.001 |
| 30–35 kg/m2 | 7849 (18.8%) | 65,593 (15.7%) | < 0.001 |
| > 35 kg/m2 | 4550 (10.9%) | 35,857 (8.6%) | < 0.001 |
| Comorbidity | |||
| Arrhythmia | 2522 (6.0%) | 22,401 (5.4%) | < 0.001 |
| Asthma | 2369 (5.7%) | 23,934 (5.7%) | 0.635 |
| CHF | 1163 (2.8%) | 9437 (2.3%) | < 0.001 |
| COPD | 1011 (2.4%) | 10,559 (2.5%) | 0.185 |
| Chronic Renal Failure | 1720 (4.1%) | 14,395 (3.4%) | < 0.001 |
| Diabetes Mellitus | 7467 (17.9%) | 64,979 (15.6%) | < 0.001 |
| Hypertension | 9848 (23.6%) | 93,046 (22.3%) | < 0.001 |
| IHD | 3367 (8.1%) | 31,677 (7.6%) | 0.001 |
| Malignancy | 3228 (7.7%) | 34,872 (8.4%) | < 0.001 |
| COVID-19 disease severity | |||
| Not hospitalized for COVID-19 | 36,248 (86.8%) | 417,570 (100.0%) | |
| Hospitalized in good condition | 2140 (5.1%) | ||
| Hospitalized in moderate condition | 818 (2.0%) | ||
| Hospitalized in severe condition | 1435 (3.4%) | ||
| Deceased | 1116 (2.7%) |
IQR Interquartile Range, BMI Body Mass Index, CHF Congestive Heart Failure, COPD Chronic Obstructive Pulmonary Disease, IHD Ischemic Heart Disease