Table 1.
Cardiovascular and sympathetic measurements at resting baseline on separate days before fentanyl or placebo administration
| Fentanyl | Placebo | P Values | |
|---|---|---|---|
| HR, beats/min | 63 ± 13 | 63 ± 14 | 0.3637 |
| Brachial MAP, mmHg | 87 ± 7 | 88 ± 8 | 0.7405 |
| Brachial SBP, mmHg | 118 ± 11 | 118 ± 12 | 0.5917 |
| Brachial DBP, mmHg | 71 ± 7 | 72 ± 8 | 0.7835 |
| MCAv, cm/s | 61 ± 15 | 60 ± 12 | 0.9368 |
| ScO2, % oxygen saturation | 59 ± 13 | 58 ± 12 | 0.9368 |
| Plasma [E], pg/mL | 22 ± 16 | 24 ± 18 | 0.5978 |
| Plasma [NE], pg/mL | 234 ± 132 | 212 ± 90 | 0.8673 |
| MSNA burst frequency, bursts/min | 14 ± 8 | 15 ± 9 | 0.6842 |
| MSNA burst incidence, bursts/100 heartbeats | 23 ± 12 | 25 ± 18 | 0.4852 |
| RR, breaths/min | 14 ± 3 | 13 ± 4 | 0.3137 |
| End-tidal CO2, mmHg | 45 ± 5 | 45 ± 6 | 0.8096 |
Values are means ± SD. DBP, diastolic blood pressure; [E], epinephrine concentration; HR, heart rate; MAP, mean arterial pressure; MCAv, middle cerebral artery velocity; MSNA, muscle sympathetic nerve activity; [NE], norepinephrine concentration; RR, respiratory rate; SBP, systolic blood pressure; ScO2, frontal cortex oxygen saturation. Paired t test used for baseline comparisons.