Table 4.
Effect of exercise intervention on the percent change (95% CI) in plasma circulating cell-free mitochondrial DNA over 4 mo
| Percent Change (95% CI) | P Value | Percent Change (95% CI)* | P Value | Percent Change (95% CI)† | P Value | |
|---|---|---|---|---|---|---|
| Overall (n = 99) | ||||||
| Usual activity | Reference | Reference | Reference | |||
| Aerobic exercise | 79.6 (8.2, 198.0) | 0.024 | 79.0 (8.0, 196.9) | 0.024 | 81.6 (8.2, 204.8) | 0.024 |
| Usual diet (n = 44) | ||||||
| Usual activity | Reference | Reference | Reference | |||
| Aerobic exercise | 5.5 (−50.1, 122.9) | 0.888 | 5.7 (−49.8, 122.5) | 0.885 | 8.0 (-49.5, 131.1) | 0.842 |
| Caloric restriction (n = 55) | ||||||
| Usual activity | Reference | Reference | Reference | |||
| Aerobic exercise | 179.7 (42.4, 449.5) | 0.003 | 177.7 (41.4, 445.2) | 0.003 | 181.7 (41.1, 462.2) | 0.003 |
*Adjusted for age, race, and sex.
†Adjusted for age, race, sex, systolic blood pressure, body mass index, diabetes, and estimated glomerular filtration rate. CI, confidence interval; n, number of participants.