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. 2021 Dec 6;322(1):F76–F88. doi: 10.1152/ajprenal.00296.2021

Figure 2.

Figure 2.

Plasma leptin and insulin concentrations in different groups of male wild-type (WT; B6) and transient receptor potential cation channel 6 (TRPC6) knockout (KO) mice before and after aortic constriction (AC) or sham surgery. A: plasma leptin concentrations in diabetes mellitus (DM), AC, and DM + AC groups of WT mice before AC or sham surgery and 8 wk after the surgery. B: plasma insulin levels in DM, AC, and DM + AC groups of WT mice before AC or sham surgery and 8 wk after the surgery. C: plasma leptin concentrations in DM, AC, and DM + AC groups of TRPC6 KO mice before AC or sham surgery and 8 wk after the surgery. D: plasma insulin concentrations in DM, AC, and DM + AC groups of TRPC6 KO mice before AC or sham surgery and 8 wk after the surgery. n = 6–8 per group. *P < 0.05 when comparing AC with DM and DM+AC groups by one-way ANOVA and Tukey’s test. B6, C57BL/6J females.