Table 3.

Heart and kidney weights in different groups of male WT and TRPC6 KO mice at 8 wk after AC or sham surgery

	WT-DM	WT-AC	WT-DM + AC	TRPC6 KO-DM	TRPC6 KO-AC	TRPC6 KO-DM + AC
Heart weight, g	0.13 ± 0.01	0.16 ± 0.01†	0.17 ± 0.02†	0.15 ± 0.01	0.19 ± 0.02†	0.18 ± 0.01†
Left kidney weight, g	0.19 ± 0.02	0.18 ± 0.01	0.19 ± 0.01	0.19 ± 0.01	0.16 ± 0.02	0.20 ± 0.01
Right kidney weight, g	0.21 ± 0.02	0.22 ± 0.01*	0.23 ± 0.02*	0.20 ± 0.01	0.20 ± 0.01*	0.23 ± 0.01*

Values are means ± SE; n = 6–9. AC, aortic constriction; DM, diabetes mellitus; KO, knockout; TRPC6, transient receptor potential cation channel 6; WT, wild-type. *P < 0.05 when comparing left and right kidney weights in the same group of WT or TRPC6 KO mice by t test. †P < 0.05 when comparing heart weight in AC and DM + AC with DM mice in WT and TRPC6 KO mice by one-way ANOVA.