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. Author manuscript; available in PMC: 2023 Jan 1.
Published in final edited form as: J Am Geriatr Soc. 2021 Oct 19;70(1):168–177. doi: 10.1111/jgs.17508

Table 2.

Type of CNS-active medication use at index for those with and without a fall-related injury

Fall-Related Injury
(N = 449)
No Fall-Related Injury
(N = 1,751)
N % N %
Specific Classes
Antidepressants 252 56 1,021 58
Opioids 139 31 523 30
Benzodiazepine/Sedative hypnotics 74 17 214 12
Skeletal muscle relaxants 14 3 59 3
Antipsychotic 2 0.4 14 0.8
Anticholinergicsa
 Genitourinary antispasmodic 63 14 170 10
 Gastrointestinal antispasmodic 22 5 126 7
 Antihistamines 6 1 31 2
 Antivertigo/Antiemetic 3 0.7 37 2
a

Some antidepressants, muscle relaxants and antipsychotics include medications with anticholinergic effects. These anticholinergic medications were included in their primary therapeutic classes and are not summarized in the anticholinergic section.